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Brinkmann Instruments tissue factor pathway inhibitor
Tissue Factor Pathway Inhibitor, supplied by Brinkmann Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tissue+factor+pathway+inhibitor/human+tissue+factor+pathway+inhibitor+gene+encoding++p151l++tfpi/10__1016_slash_s2352___3026_ascii40_24_ascii41_00348___x-62-13-1
Average 90 stars, based on 1 article reviews
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Article Snippet: Subscriber access provided by NEW YORK UNIV Journal of Proteome Research is published by the American Chemical Society.. 1155 Sixteenth Street N.W., Washington, DC 20036 Published by American Chemical Society.. Copyright © American Chemical Society.

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Effect of angiogenesis inhibitors on bone marrow cells from female C57BL/6N mice. (a) Schematic illustration of ex‐vivo experimental design. (b) Effect of pazopanib (VEGF inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (c) Effect of pioglitazone (osteopontin inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (d) Effect of epicatechin (ADAMTS‐1 inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (e) Effect of rmTFPI (tissue factor pathway inhibitor) on the inhibition tEVs‐induced bone marrow cell proliferation. The cells were treated either inhibitors alone or with inhibitors in combination with 5e9 tEVs. The data are presented as means (±SD, n = 3). Statistical significance (* p < 0.01, *** p < 0.001, and **** p < 0.0001) between experimental groups was calculated with using one‐way analysis of variance (ANOVA) with each value Tukey's multiple comparisons test.
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Effect of angiogenesis inhibitors on bone marrow cells from female C57BL/6N mice. (a) Schematic illustration of ex‐vivo experimental design. (b) Effect of pazopanib (VEGF inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (c) Effect of pioglitazone (osteopontin inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (d) Effect of epicatechin (ADAMTS‐1 inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (e) Effect of rmTFPI (tissue factor pathway inhibitor) on the inhibition tEVs‐induced bone marrow cell proliferation. The cells were treated either inhibitors alone or with inhibitors in combination with 5e9 tEVs. The data are presented as means (±SD, n = 3). Statistical significance (* p < 0.01, *** p < 0.001, and **** p < 0.0001) between experimental groups was calculated with using one‐way analysis of variance (ANOVA) with each value Tukey's multiple comparisons test.
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Effect of angiogenesis inhibitors on bone marrow cells from female C57BL/6N mice. (a) Schematic illustration of ex‐vivo experimental design. (b) Effect of pazopanib (VEGF inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (c) Effect of pioglitazone (osteopontin inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (d) Effect of epicatechin (ADAMTS‐1 inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (e) Effect of rmTFPI (tissue factor pathway inhibitor) on the inhibition tEVs‐induced bone marrow cell proliferation. The cells were treated either inhibitors alone or with inhibitors in combination with 5e9 tEVs. The data are presented as means (±SD, n = 3). Statistical significance (* p < 0.01, *** p < 0.001, and **** p < 0.0001) between experimental groups was calculated with using one‐way analysis of variance (ANOVA) with each value Tukey's multiple comparisons test.

Journal: Journal of Extracellular Vesicles

Article Title: Extracellular vesicles originating from melanoma cells promote dysregulation in haematopoiesis as a component of cancer immunoediting

doi: 10.1002/jev2.12471

Figure Lengend Snippet: Effect of angiogenesis inhibitors on bone marrow cells from female C57BL/6N mice. (a) Schematic illustration of ex‐vivo experimental design. (b) Effect of pazopanib (VEGF inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (c) Effect of pioglitazone (osteopontin inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (d) Effect of epicatechin (ADAMTS‐1 inhibitor) on the inhibition of tEVs‐induced bone marrow cell proliferation. (e) Effect of rmTFPI (tissue factor pathway inhibitor) on the inhibition tEVs‐induced bone marrow cell proliferation. The cells were treated either inhibitors alone or with inhibitors in combination with 5e9 tEVs. The data are presented as means (±SD, n = 3). Statistical significance (* p < 0.01, *** p < 0.001, and **** p < 0.0001) between experimental groups was calculated with using one‐way analysis of variance (ANOVA) with each value Tukey's multiple comparisons test.

Article Snippet: The inhibitory effect of pazopanib, a VEGFR inhibitor (SML3076, Sigma‐Aldrich, Germany), pioglitazone, an osteopontin inhibitor (E6910, Sigma‐Aldrich, Germany), epigallocatechin, an ADAMTS‐1 inhibitor (E3768, Sigma‐Aldrich, Germany), and rmTFPI Protein, a recombinant mouse tissue factor pathway inhibitor (2975‐PI, R&D Systems) were evaluated to assess their abilities to prevent the possible impact of tEVs on the hematopoietic.

Techniques: Ex Vivo, Inhibition